Multi-drug resistance of pathogenic microorganisms is becoming a serious threat, particularly to immunocompromised populations. The high mortality of systematic fungal infections necessitates novel antifungal drugs and therapies. Unfortunately, with traditional drug discovery approaches, only echinocandins was approved by FDA as a new class of antifungals in the past two decades. Drug efflux is...

Hepatitis delta is considered the most severe form of viral hepatitis, but variables associated with disease progression are poorly defined. This study aimed to identify risk factors associated with worse clinical outcome in patients with hepatitis delta and to develop a clinical score to determine their risk of experiencing liver-related morbidity or mortality. We followed 75 HBsAg-anti-HDV-po...

The present study aimed to investigate the role of beauveria (BEA) in asthma. We investigated the cytotoxic effect of BEA on the proliferation of inflammatory cells and secretion of inflammatory mediators both in-vitro and in-vivo. In in-vitro studies, BEA inhibited lymphocytic cell proliferation and the proliferation of lymphocytic cells induced by Phorbol-12-myristate-13-acetate (PMA). We use...

crack identification is a very important issue in mechanical systems, because it is a damage that if develops may cause catastrophic failure. in the first part of this research, modal analysis of a multi-cracked variable cross-section beam is done using finite element method. then, the obtained results are validated usingthe results of experimental modal analysis tests. in the next part, a nove...

We present a proactive resource allocation algorithm, called BEA, for faulttolerant asynchronous real-time distributed systems. BEA considers an application model where trans-node application timeliness requirements are expressed using benefit functions, and anticipated workload during future time intervals are expressed using adaptation functions. Furthermore, BEA considers an adaptation model...

Female Swiss ICR mice were injected ip with 100 or 300 mg 2-bromoethylamine hydrobromide (BEA)/kg body weight. Male Swiss ICR mice were subjected to water deprivation, or treated with 5% dextrose in water, dimethylsulphoxide, piperonyl butoxide, SKF-525A, sodium phenobarbital, beta-naphthoflavone, probenecid, reserpine, diethyl maleate, buthionine sulphoximine or L-cysteine. Urine collected seq...

Crack identification is a very important issue in mechanical systems, because it is a damage that if develops may cause catastrophic failure. In the first part of this research, modal analysis of a multi-cracked variable cross-section beam is done using finite element method. Then, the obtained results are validated usingthe results of experimental modal analysis tests. In the next part, a nove...

Rats injected with a single, 50-mg dose of bromoethylamine (BEA) developed papillary necrosis accompanied by sever interstitial fibrosis. At 1 mo, the creatinine clearance decreased (control 0.66 versus BEA 0.33 ml/min per 100 g body wt, P = 0.02), and the urine albumin-to-creatinine ratio increased markedly (control 0.19 versus BEA 0.51, P = 0.02). In a group of animals given the angiotensin-c...

This is a prospective study conducted in December 2012 among 128 at the Nianankoro Fomba Hospital in Segou in order to assess their knowledge and practices on Blood Exposure Accidents (BEA). The average age of caregivers was 35.4 ± 9 years (range: 22-59 years). The nurses were predominant with 37.5%. The definition of BEA was mastered by 43.8%. The main transmissible infectious agents (HIV, HBV...

This work presents the hydrogen production from steam gasification of palm kernel shell (PKS) at 700 C in the presence of 5% Ni/BEA and 5% Fe/BEA as catalysts. The steam gasification was performed in two-staged reactors to evaluate the effect of calcinations temperature and the steam to biomass ratio on the product gas composition. The catalytic activity of Ni/BEA catalyst decreases with increa...